Cover Your Mouth and Nose When you sneeze or cough, always cover your mouth and nose with a tissue, and throw the used tissue in the trash. If you do not have time to find a tissue, sneeze or cough into the crook of your elbow or upper arm. Do not cover your mouth with your hands. Wash Your Hands Keeping your hands clean is an easy and effective way to reduce the spread of germs. Wash your hands often with regular soap and water or an alcohol-based hand rub. Thorough hand washing will help prevent illness for you and those around you. Stay Home When Sick Help yourself and others by staying home when you are sick. It is important to avoid contact with others when you are most contagious. The time when you are most contagious varies depending on your illness. The stress of work or school may make your illness worse or prolong your symptoms. Staying home and getting some rest may help you to get well sooner.