Honors
Bio Review Questions Midterm C 2004-05
Modified
True/False
Indicate
whether the sentence or statement is true or false. If false, change the identified word or
phrase to make the sentence or statement true.
____ 1. People have used selective breeding to
produce many different dog breeds. _________________________
____ 2. Without genetic engineering, horses
would not have been domesticated. ______________________________
____ 3. Without selective breeding, dogs today would
probably be less similar. _________________________
____ 4. Hybrids are often hardier than either
of their parents. _________________________
____ 5. Animal breeders maintain cat and dog breeds
by the process of hybridization. _________________________
____ 6. Exposing a population of plants to radiation
or certain chemicals can increase the frequency of mutations that occur
within the population. _________________________
____ 7. A polyploid plant has more than two copies of
each gene. _________________________
____ 8. During DNA sequencing, if all the bands on an
electrophoresis gel are the same color, the single-stranded DNA sample
consisted of one kind of fragment. _________________________
____ 9. To transform a plant, scientists inject DNA
into an adult plant. _________________________
____ 10. To produce a recombinant plasmid, the plasmid
and the foreign DNA are cut with a different restriction enzyme.
_________________________
____ 11. Scientists use genetic markers to
determine which animal cells have been successfully transformed.
_________________________
____ 12. Bacterial cells that have been transformed
with a plasmid that carries a genetic marker for resistance to the antibiotic
tetracycline will not survive in a culture treated with tetracycline.
_________________________
____ 13. The fact that human genes inserted into
bacteria produce proteins shows that the basic mechanisms of gene expression
are different in bacteria and humans. _________________________
____ 14. Some transgenic animals grow faster
because they have extra copies of growth hormone genes.
_________________________
____ 15. To produce Dolly, Ian Wilmut removed the
nucleus from a sheep’s body cell and fused it with a cell taken from
another adult. _________________________
____ 16. In a human karyotype, 44 of the chromosomes
are autosomes. _________________________
____ 17. In a human karyotype, 23 chromosome
pairs are similar in size and shape. _________________________
____ 18. In humans, the mother determines the
sex of the offspring. _________________________
____ 19. In a pedigree, if a mother is represented by a
shaded circle and a father is represented by a shaded square, their children
cannot be represented by half-shaded circles or squares.
_________________________
____ 20. A pedigree showing the inheritance of
Huntington’s disease within a family would not show any half-shaded
symbols. _________________________
____ 21. If a person has blood type A, he or she cannot
receive a blood transfusion from a person with blood type O.
_________________________
____ 22. Two parents who have Huntington’s disease may
produce an offspring who does not have Huntington’s disease.
_________________________
____ 23. Chromosome 22 contains long stretches
of DNA that do not code for proteins. _________________________
____ 24. A dominant X-linked trait would be more
common in males than in females. _________________________
____ 25. If a cat has both orange and black spots, it
is homozygous for the alleles on the X chromosome that code for spot
color. _________________________
____ 26. A person who has Down syndrome has two
copies of chromosome 21. _________________________
____ 27. Males generally do not have Barr
bodies. _________________________
____ 28. DNA fingerprinting analyzes sections of DNA
that have little or no known function but are similar from person to
person. _________________________
____ 29. To locate genes within the human DNA sequence,
scientists look for open reading frames within the sequence.
_________________________
____ 30. Information from the Human Genome Project can
be used to learn more about human diseases. _________________________
____ 31. After his voyage on the Beagle, Charles
Darwin wondered whether similar species from the Galápagos Islands could once
have been members of the same species. _________________________
____ 32. Charles Darwin came to realize that organisms
of the same species are identical. _________________________
____ 33. According to Lamarck, the sea floor can
be pushed up to form mountains by forces within Earth.
_________________________
____ 34. In Charles Darwin’s time, many people thought
that Earth and its living things were formed about a few thousand years
ago. _________________________
____ 35. Evidence that the surface of a mountain was
once under the sea includes the presence of marine fossils on the
mountain. _________________________
____ 36. Lyell hypothesized that human
populations are kept in check by war, disease, and famine.
_________________________
____ 37. In 1858, Alfred Russel Wallace sent Charles
Darwin an essay proposing an explanation for evolution that was very
similar to Darwin’s. _________________________
____ 38. Artificial selection as practiced by farmers
is also called natural selection. _________________________
____ 39. In natural selection, human breeders,
rather than the environment, select the variations of traits to be passed to
offspring. ______________________________
____ 40. According to Darwin, the word selection
would be applied to organisms adapted to survive and reproduce in their
particular environments. _________________________
____ 41. The term “fitness” refers to an
organism’s ability to survive and reproduce in a specific environment.
_________________________
____ 42. The fact that species today look different
from their ancestors can be described as descent with modification.
_________________________
____ 43. According to the concept of natural
variation, living and extinct species evolved from the same ancestors.
______________________________
____ 44. According to Charles Darwin, individuals best
suited to their environment survive and reproduce most successfully.
_________________________
____ 45. According to Charles Darwin, members of a
species must share limited resources. _________________________
____ 46. Because all members of a population can interbreed,
biologists often study their genes as a single group. _________________________
____ 47. In a gene pool, as the relative frequency of
one allele for a trait increases, the relative frequencies of other alleles for
that trait decrease. _________________________
____ 48. Most inheritable differences are due to mutations
that occur during the production of gametes. _________________________
____ 49. Mutations do not always affect an organism’s genotype—its
physical, behavioral, and biochemical characteristics.
_________________________
____ 50. A polygenic trait is controlled by one
gene. _________________________
____ 51. On a graph, the distribution of phenotypes for
a single-gene trait tends to form a bell-shaped curve.
_________________________
____ 52. Natural selection on single-gene traits
can lead to changes in allele frequencies. _________________________
____ 53. In a population of snakes with a range of body
lengths, if the longest individuals have the highest fitness, disruptive
selection is likely to occur. _________________________
____ 54. In small populations, an allele can
become more or less common simply by chance. _________________________
____ 55. Genetic drift may occur when a small
group of individuals colonize a new habitat. _________________________
____ 56. When mutations introduce new alleles into a
population, genetic variation is disrupted. _________________________
____ 57. In a population of birds, if females prefer
males with long tails, the population violates the condition of directional
selection described by the Hardy-Weinberg principle.
_________________________
____ 58. In the type of reproductive isolation called behavioral
isolation, two populations are separated by barriers such as rivers or
mountains. _________________________
____ 59. Two populations that have overlapping ranges
can remain reproductively isolated through behavioral isolation or
temporal isolation from each other. _________________________
____ 60. The first step of the speciation of the
Galápagos finches likely was the arrival of founders from South America.
_________________________
Multiple
Choice
Identify
the letter of the choice that best completes the statement or answers the
question.
____ 61. Luther Burbank produced over 800 varieties of
plants by
|
a. |
genetic engineering. |
|
b. |
transformation. |
|
c. |
selective breeding. |
|
d. |
DNA sequencing. |
____ 62. Which of the following have been produced by
selective breeding?
|
a. |
horse breeds |
|
b. |
cat breeds |
|
c. |
dog breeds |
|
d. |
all of the above |
____ 63. Selective breeding produces
|
a. |
more offspring. |
|
b. |
fewer offspring. |
|
c. |
desired traits in offspring. |
|
d. |
transgenic organisms. |
____ 64. Which of the following is NOT an example of
selective breeding?
|
a. |
allowing only the best milk-producing
cows to reproduce |
|
b. |
crossing disease-resistant plants with
plants that produce high food yields |
|
c. |
mating cats that have long hair with
cats that have long tails |
|
d. |
allowing dogs to mate only once a year |
____ 65. Which of the following is most likely to bring
together two recessive alleles for a genetic defect?
|
a. |
inbreeding |
|
b. |
hybridization |
|
c. |
genetic engineering |
|
d. |
transformation |
____ 66. To make a new line of plants, Burbank used the
process of
|
a. |
inbreeding. |
|
b. |
hybridization. |
|
c. |
transformation. |
|
d. |
genetic engineering. |
____ 67. The crossing of buffalo and cattle to produce
beefalo is an example of
|
a. |
inbreeding. |
|
b. |
hybridization. |
|
c. |
genetic engineering. |
|
d. |
transformation. |
____ 68. Which of the following statements is NOT true?
|
a. |
Inbreeding and hybridization are
opposite processes. |
|
b. |
A hybrid plant has all the
characteristics of both its parents. |
|
c. |
Inbreeding can produce an offspring that
has a defect that neither parent shows. |
|
d. |
Hybridization is used to produce new
varieties of plants and animals. |
____ 69. Scientists produced oil-eating bacteria by
|
a. |
making bacteria polyploid. |
|
b. |
inbreeding bacteria. |
|
c. |
inducing mutations in bacteria. |
|
d. |
hybridizing bacteria. |
____ 70. What is the ultimate source of genetic
variability?
|
a. |
inbreeding |
|
b. |
radiation |
|
c. |
hybridization |
|
d. |
mutations |
____ 71. Breeders induce mutations in organisms to
|
a. |
increase diversity in populations. |
|
b. |
make organisms more alike. |
|
c. |
avoid selective breeding. |
|
d. |
produce organisms with undesirable
characteristics. |
____ 72. Which of the following includes all the
others?
|
a. |
hybridization |
|
b. |
inbreeding |
|
c. |
selective breeding |
|
d. |
induced mutations |
____ 73. Polyploidy instantly results in a new plant
species because it
|
a. |
changes a species’ number of
chromosomes. |
|
b. |
produces a hardier species. |
|
c. |
causes mutations. |
|
d. |
all of the above |
____ 74. Mutations are useful in selective breeding
because they
|
a. |
help maintain the desired
characteristics of animal breeds. |
|
b. |
are usually found in hybrids. |
|
c. |
are usually beneficial. |
|
d. |
can be used to enhance the process of
hybridization. |

Figure 13-1
____ 75. What does Figure 13-1 show?
|
a. |
gel electrophoresis |
|
b. |
DNA sequencing |
|
c. |
a restriction enzyme producing a DNA
fragment |
|
d. |
polymerase chain reaction |
____ 76. In Figure 13-1, between which nucleotides is
the DNA cut?
|
a. |
adenine and thymine |
|
b. |
cytosine and guanine |
|
c. |
thymine and cytosine |
|
d. |
adenine and guanine |
____ 77. One function of gel electrophoresis is to
|
a. |
separate DNA fragments. |
|
b. |
cut DNA. |
|
c. |
recombine DNA. |
|
d. |
extract DNA. |
____ 78. The process of making changes in the DNA code
of a living organism is called
|
a. |
selective breeding. |
|
b. |
genetic engineering. |
|
c. |
inbreeding. |
|
d. |
hybridization. |
____ 79. A DNA molecule produced by combining DNA from
different sources is known as
|
a. |
a mutant. |
|
b. |
a hybrid. |
|
c. |
a polyploid. |
|
d. |
recombinant DNA. |
____ 80. Knowing the sequence of an organism’s DNA
allows researchers to
|
a. |
reproduce the organism. |
|
b. |
mutate the DNA. |
|
c. |
study specific genes. |
|
d. |
cut the DNA. |
____ 81. Analyzing DNA by gel electrophoresis allows
researchers to
|
a. |
identify similarities and differences in
the genomes of different kinds of organisms. |
|
b. |
determine whether a particular allele of
a gene is dominant or recessive. |
|
c. |
compare the phenotypes of different
organisms. |
|
d. |
cut DNA with restriction enzymes. |
____ 82. On an electrophoresis gel, band B is closer to
the positive end of the gel than is band A. Which of the following statements
is true?
|
a. |
Band B is more negatively charged than
band A. |
|
b. |
Band B moved faster than band A. |
|
c. |
Band A is smaller than band B. |
|
d. |
Band B consists of larger DNA fragments
than does band A. |
____ 83. Genetic engineering involves
|
a. |
reading a DNA sequence. |
|
b. |
editing a DNA sequence. |
|
c. |
reinserting DNA into living organisms. |
|
d. |
all of the above |
____ 84. Which of the following are NOT used to read
DNA sequences?
|
a. |
nucleotides |
|
b. |
gels |
|
c. |
fluorescent dyes |
|
d. |
double-stranded DNA molecules |
____ 85. Suppose a restriction enzyme recognizes the
six-base sequence
|
AAGCTT |
|
TTCGAA |
in a double strand of DNA. Between which two nucleotides on each strand
would the enzyme have to cut to produce a fragment with sticky ends that are
four bases long?
|
a. |
GC |
|
b. |
CT |
|
c. |
AA |
|
d. |
AG |
____ 86. If two DNA samples showed an identical pattern
and thickness of bands produced by gel electrophoresis, the samples contained
|
a. |
the same amount of DNA. |
|
b. |
fragments of the same size. |
|
c. |
the same DNA molecules. |
|
d. |
all of the above |
____ 87. During transformation,
|
a. |
a prokaryote is changed into a
eukaryote. |
|
b. |
a cell takes in DNA from outside the
cell. |
|
c. |
foreign DNA is inserted into a plasmid. |
|
d. |
a cell is mutated. |
____ 88. Scientists can transform plant cells by
|
a. |
using the bacterium Agrobacterium
tumefaciens. |
|
b. |
removing the plant cell walls and then
mixing the cells with DNA. |
|
c. |
injecting DNA into the plant cells. |
|
d. |
all of the above |
____ 89. A recombinant plasmid gets inside a bacterial
cell by
|
a. |
inducing mutations. |
|
b. |
injecting itself into the cell. |
|
c. |
transformation. |
|
d. |
recombining with the cell. |
____ 90. Which of the following includes all the
others?
|
a. |
plasmid |
|
b. |
transformed bacterium |
|
c. |
foreign gene |
|
d. |
recombinant DNA |
____ 91. Which of the following steps is NOT essential
in producing recombinant DNA?
|
a. |
Cut out a piece of DNA from a DNA
molecule. |
|
b. |
Splice a piece of DNA into DNA from
another organism. |
|
c. |
Use a restriction enzyme to form sticky
ends in DNA. |
|
d. |
Read the DNA sequence of the piece of
DNA to be cut and spliced. |
____ 92. A gene that makes it possible to distinguish
bacteria that carry a plasmid (and the foreign DNA) from those that don’t is
called a(an)
|
a. |
resistance gene. |
|
b. |
antibiotic. |
|
c. |
genetic marker. |
|
d. |
clone. |
____ 93. Which of the following is often used as a
genetic marker?
|
a. |
a foreign gene |
|
b. |
a gene for antibiotic resistance |
|
c. |
a DNA sequence that serves as a
bacterial origin of replication |
|
d. |
a nucleotide labeled with a fluorescent
dye |
____ 94. The transformation of a plant cell is
successful if
|
a. |
the plasmid that entered the cell
reproduces inside the cell. |
|
b. |
the foreign DNA is integrated into one
of the cell’s chromosomes. |
|
c. |
the cell reproduces. |
|
d. |
a plasmid has entered the cell. |
____ 95. Which of the following is an example of
successful transformation?
|
a. |
injection of bacterial DNA into plant
cells |
|
b. |
a defective gene in a cell being
replaced with a normal gene |
|
c. |
bacterial cells taking in plasmids that
have a genetic marker |
|
d. |
none of the above |
____ 96. Suppose a bacterial culture were mixed with
recombinant plasmids containing a gene for resistance to penicillin. The
bacterial culture was then treated with penicillin. Which of the following
statements is NOT true?
|
a. |
Those bacteria that contain the plasmid
will survive. |
|
b. |
The penicillin will kill the bacteria
that were transformed. |
|
c. |
The gene for antibiotic resistance is
expressed in the bacteria that survive. |
|
d. |
Those bacteria that are successfully
transformed will survive. |
____ 97. What kind of technique do scientists use to
make transgenic organisms?
|
a. |
hybridization |
|
b. |
inbreeding |
|
c. |
inducing of mutations |
|
d. |
genetic engineering |
____ 98. What is an advantage of using transgenic
bacteria to produce human proteins?
|
a. |
The human proteins produced by
transgenic bacteria work better than those produced by humans. |
|
b. |
Transgenic bacteria can produce human
proteins in large amounts. |
|
c. |
The human proteins produced by
transgenic bacteria last longer than those produced by humans. |
|
d. |
Transgenic bacteria can produce human
proteins used to make plastics. |
____ 99. What has been an advantage of producing
transgenic plants?
|
a. |
increasing the food supply |
|
b. |
using more pesticides |
|
c. |
producing clones |
|
d. |
studying human genes |
____ 100. To produce transgenic bacteria that
make insulin, which of the following steps did scientists have to take first?
|
a. |
Insert the human insulin gene into a
plasmid. |
|
b. |
Extract the insulin from the bacterial
culture. |
|
c. |
Use a restriction enzyme to cut out the
insulin gene from human DNA. |
|
d. |
Transform bacteria with the recombinant
plasmid. |
____ 101. What are scientists more likely to
learn from transgenic animals than from transgenic bacteria or transgenic
plants?
|
a. |
the structure of human proteins |
|
b. |
the process of cloning |
|
c. |
how human genes function |
|
d. |
how plasmids reproduce |
____ 102. The Scottish scientist Ian Wilmut
cloned a
|
a. |
bacterium. |
|
b. |
sheep. |
|
c. |
plant. |
|
d. |
cow. |
____ 103. Which of the following is a clone?
|
a. |
the adult female sheep whose DNA was
used to produce Dolly |
|
b. |
a transgenic mouse |
|
c. |
a bacterium taken from a bacterial
colony |
|
d. |
the tobacco plant with the luciferase
gene |
____ 104. What kind of cell (or cells) was
used to make Dolly?
|
a. |
body cell only |
|
b. |
egg cell only |
|
c. |
egg cell and sperm cell |
|
d. |
body cell and egg cell |
____ 105. Why is Dolly a clone?
|
a. |
The source of her DNA was a single body
cell. |
|
b. |
The DNA molecules in all her cells are
identical. |
|
c. |
She was produced using the DNA from an
adult’s egg cell. |
|
d. |
She is genetically identical to her
offspring. |
____ 106. How many chromosomes are shown in a
normal human karyotype?
|
a. |
2 |
|
b. |
23 |
|
c. |
44 |
|
d. |
46 |
____ 107. Which of the following are shown in
a karyotype?
|
a. |
homologous
chromosomes |
|
b. |
sex
chromosomes |
|
c. |
autosomes |
|
d. |
all of
the above |
____ 108. Which of the following can be
observed in a karyotype?
|
a. |
a change
in a DNA base |
|
b. |
an extra
chromosome |
|
c. |
genes |
|
d. |
alleles |
____ 109. In humans, a male has
|
a. |
one X chromosome only. |
|
b. |
two X chromosomes. |
|
c. |
one X chromosome and one Y chromosome. |
|
d. |
two Y chromosomes. |
____ 110. Human females produce egg cells that
have
|
a. |
one X
chromosome. |
|
b. |
two X
chromosomes. |
|
c. |
one X or
one Y chromosome. |
|
d. |
one X
and one Y chromosome. |
____ 111. What is the approximate probability
that a human offspring will be female?
|
a. |
10% |
|
b. |
25% |
|
c. |
50% |
|
d. |
75% |
____ 112. What percentage of human sperm cells
carry an X chromosome?
|
a. |
0% |
|
b. |
25% |
|
c. |
50% |
|
d. |
100% |
____ 113. A human female inherits
|
a. |
one copy
of every gene located on each of the X chromosomes. |
|
b. |
twice as
many sex chromosomes as a human male inherits. |
|
c. |
one copy
of every gene located on the Y chromosome. |
|
d. |
all of
the same genes that a human male inherits. |
____ 114. In a pedigree, a circle represents
a(an)
|
a. |
male. |
|
b. |
female. |
|
c. |
child. |
|
d. |
adult. |
____ 115. A pedigree CANNOT be used to
|
a. |
determine
whether a trait is inherited. |
|
b. |
show how
a trait is passed from one generation to the next. |
|
c. |
determine
whether an allele is dominant or recessive. |
|
d. |
none of
the above |
____ 116. Which of the following would you be
least likely to see in a pedigree?
|
a. |
All of
the symbols are unshaded. |
|
b. |
All of
the symbols are shaded. |
|
c. |
All of
the symbols are half-shaded. |
|
d. |
About
half of the symbols are circles. |
____ 117. Which of the following is caused by
a dominant allele?
|
a. |
Huntington’s
disease |
|
b. |
PKU |
|
c. |
Tay-Sachs
disease |
|
d. |
none of
the above |
____ 118. Which of the following is determined
by multiple alleles?
|
a. |
Rh blood
group |
|
b. |
ABO
blood group |
|
c. |
PKU |
|
d. |
Huntington’s
disease |
____ 119. A person who has PKU
|
a. |
inherited
the recessive allele for the trait from one parent. |
|
b. |
inherited
the recessive allele for the trait from both parents. |
|
c. |
is
heterozygous for the trait. |
|
d. |
will not
pass the allele for the trait to his or her offspring. |
____ 120. Which of the following genotypes
result in the same phenotype?
|
a. |
IAIA and IAIB |
|
b. |
IBIB and IBi |
|
c. |
IBIB and IAIB |
|
d. |
IBi
and ii |
____ 121. If a man with blood type A and a
woman with blood type B produce an offspring, what might be the offspring’s
blood type?
|
a. |
AB or O |
|
b. |
A, B, or
O |
|
c. |
A, B,
AB, or O |
|
d. |
AB only |
____ 122. Which of the following statements is
NOT true?
|
a. |
A person
with Huntington’s disease might not pass the allele for the disease to his or
her offspring. |
|
b. |
A person
with Huntington’s disease might be homozygous for the disease. |
|
c. |
Huntington’s
disease is caused by a recessive allele. |
|
d. |
A person
who inherits one allele for Huntington’s disease will develop the disease. |
____ 123. Sickle cell disease is caused by a
|
a. |
change
in one DNA base. |
|
b. |
change
in the size of a chromosome. |
|
c. |
change
in two genes. |
|
d. |
change
in the number of chromosomes in a cell. |
____ 124. In cystic fibrosis, a change in a
single gene causes the protein called CFTR to
|
a. |
become
less soluble. |
|
b. |
fold
improperly. |
|
c. |
destroy
the cell membrane. |
|
d. |
transport
sodium ions instead of chloride ions. |
____ 125. Compared with normal hemoglobin, the
hemoglobin of a person with sickle cell disease
|
a. |
is
longer. |
|
b. |
is
shorter. |
|
c. |
has a
different sequence of amino acids. |
|
d. |
is
wider. |
____ 126. Which of the following does NOT lead
to cystic fibrosis?
|
a. |
missing
codon in mRNA |
|
b. |
shorter
CFTR polypeptide chain |
|
c. |
point
mutation |
|
d. |
absence
of CFTR in cell membrane |
____ 127. People who are heterozygous for
sickle cell disease are generally healthy because
|
a. |
they are
resistant to malaria. |
|
b. |
they
usually have some normal hemoglobin in their red blood cells. |
|
c. |
their
abnormal hemoglobin usually doesn’t cause their red blood cells to become
sickle-shaped. |
|
d. |
they do
not produce abnormal hemoglobin. |
____ 128. The sequencing of human chromosomes
21 and 22 showed that
|
a. |
some
regions of chromosomes do not code for proteins. |
|
b. |
all of
the DNA of chromosomes codes for proteins. |
|
c. |
different
chromosomes have the same number of genes. |
|
d. |
different
chromosomes contain the same number of DNA bases. |
____ 129. Alleles found on the same
chromosomes
|
a. |
are
dominant. |
|
b. |
are
never separated by recombination. |
|
c. |
are
linked. |
|
d. |
contain
repetitive DNA. |
____ 130. The long stretches of repetitive DNA
in chromosomes 21 and 22 are unstable sites
|
a. |
that
contain genes. |
|
b. |
where
rearrangements occur. |
|
c. |
that
cause genetic disorders. |
|
d. |
that do
not allow crossing-over to occur. |
____ 131. Many sex-linked genes are located on
|
a. |
the
autosomes. |
|
b. |
the X
chromosome only. |
|
c. |
the Y
chromosome only. |
|
d. |
both the
X chromosome and the Y chromosome. |
____ 132. Colorblindness is more common in
males than in females because
|
a. |
fathers
pass the allele for colorblindness to their sons only. |
|
b. |
the
allele for colorblindness is located on the Y chromosome. |
|
c. |
the
allele for colorblindness is recessive and located on the X chromosome. |
|
d. |
males
who are colorblind have two copies of the allele for colorblindness. |
____ 133. Which of the following statements is
true?
|
a. |
Females
cannot have hemophilia. |
|
b. |
The
father of a colorblind boy may be colorblind. |
|
c. |
A
sex-linked allele cannot be dominant. |
|
d. |
The
mother of a colorblind boy must be colorblind. |
____ 134. Which of the following form(s) a
Barr body?
|
a. |
the Y
chromosome in a male cell |
|
b. |
the X
chromosome in a male cell |
|
c. |
one of
the X chromosomes in a female cell |
|
d. |
both of
the X chromosomes in a female cell |
____ 135. The formation of a Barr body
|
a. |
causes
the genes on one of the X chromosomes in a female cell to be switched off. |
|
b. |
always
causes the same X chromosome in a female’s cells to be switched off. |
|
c. |
switches
on the Y chromosome in a male cell. |
|
d. |
none of
the above |
____ 136. A cat that has spots of only one
color
|
a. |
has no
Barr bodies. |
|
b. |
must be
a male. |
|
c. |
must be
a female. |
|
d. |
may be a
male or a female. |
____ 137. The failure of chromosomes to
separate during meiosis is called
|
a. |
nondisjunction. |
|
b. |
X-chromosome
inactivation. |
|
c. |
Turner’s
syndrome. |
|
d. |
Down
syndrome. |
____ 138. Because the X chromosome contains
genes that are vital for normal development, no baby has been born
|
a. |
with one
X chromosome. |
|
b. |
with
three X chromosomes. |
|
c. |
without
an X chromosome. |
|
d. |
with
four X chromosomes. |
____ 139. Which of the following combinations
of sex chromosomes represents a female?
|
a. |
XY |
|
b. |
XXY |
|
c. |
XXXY |
|
d. |
XX |
____ 140. If nondisjunction occurs during
meiosis,
|
a. |
only two
gametes may form instead of four. |
|
b. |
some
gametes may have an extra copy of some genes. |
|
c. |
the
chromatids do not separate. |
|
d. |
it
occurs during prophase. |
____ 141. Nondisjunction can involve
|
a. |
autosomes. |
|
b. |
sex
chromosomes. |
|
c. |
homologous
chromosomes. |
|
d. |
all of
the above |
____ 142. Scientists test for alleles that
cause human genetic disorders by
|
a. |
making
karyotypes. |
|
b. |
making
DNA fingerprints. |
|
c. |
detecting
the DNA sequences found in those alleles. |
|
d. |
making
pedigrees. |
____ 143. The process of DNA fingerprinting is
based on the fact that
|
a. |
the most
important genes are different among most people. |
|
b. |
no two
people, except identical twins, have exactly the same DNA. |
|
c. |
most
genes are dominant. |
|
d. |
most
people have DNA that contains repeats. |
____ 144. What conclusion CANNOT be made from
two DNA fingerprints that show identical patterns of bands?
|
a. |
The DNA
from the two DNA fingerprints almost certainly came from the same person. |
|
b. |
The DNA
from the two DNA fingerprints definitely came from two different people. |
|
c. |
The DNA
from the two DNA fingerprints definitely came from the same person. |
|
d. |
The DNA
repeats that formed the bands in each DNA fingerprint are the same length. |
____ 145. The Human Genome Project is an
attempt to
|
a. |
make a
DNA fingerprint of every person’s DNA. |
|
b. |
sequence
all human DNA. |
|
c. |
cure
human diseases. |
|
d. |
identify
alleles in human DNA that are recessive. |
____ 146. The human genome was sequenced
|
a. |
by
sequencing each gene on each chromosome, one at a time. |
|
b. |
using
DNA fingerprinting. |
|
c. |
by
looking for overlapping regions between sequenced DNA fragments. |
|
d. |
using
open reading frames. |
____ 147. Which of the following information
CANNOT be obtained from the Human Genome Project?
|
a. |
causes
of genetic disorders |
|
b. |
amino
acid sequences of human proteins |
|
c. |
locations
of genes on chromosomes |
|
d. |
whether
an allele is dominant or recessive |
____ 148. The purpose of gene therapy is to
|
a. |
cure
genetic disorders. |
|
b. |
determine
the sequences of genes. |
|
c. |
remove
mutations from genes. |
|
d. |
change
dominant alleles to recessive alleles. |
____ 149. Which of the following is the first
step in gene therapy?
|
a. |
splicing
the normal gene to viral DNA |
|
b. |
allowing
recombinant viruses to infect human cells |
|
c. |
using
restriction enzymes to cut out the normal gene from DNA |
|
d. |
identifying
the faulty gene that causes the disease |
____ 150. Gene therapy is successful if the
|
a. |
viruses
carrying the replacement gene infect the person’s cells. |
|
b. |
replacement
gene is replicated in the person’s cells. |
|
c. |
replacement
gene is transcribed in the person’s cells. |
|
d. |
replacement
gene is successfully spliced to viral DNA. |
____ 151. During his voyage on the Beagle,
Charles Darwin made many observations
|
a. |
in England. |
|
b. |
in North America. |
|
c. |
on the Galápagos Islands. |
|
d. |
in Asia. |
____ 152. On the Galápagos Islands, Charles
Darwin observed
|
a. |
completely unrelated species on each of
the islands. |
|
b. |
species exactly like those found in
South America. |
|
c. |
somewhat similar species, with traits
that suited their particular environments. |
|
d. |
species completely unrelated to those
found in South America. |
____ 153. The species of finches that Charles
Darwin found on the Galápagos Islands displayed different structural
adaptations. One of the adaptations that Darwin noted was the
|
a. |
similarities of the birds’ embryos. |
|
b. |
birds’ different-shaped beaks. |
|
c. |
length of the birds’ necks. |
|
d. |
number of eggs in each bird’s nest. |
____ 154. Based on the adaptations Charles
Darwin observed in finches and tortoises in the Galápagos, he wondered
|
a. |
if species living on different islands
had once been members of the same species. |
|
b. |
if finches and tortoises had originated
from the same ancestral species. |
|
c. |
if all birds on the different islands
were finches. |
|
d. |
why all tortoises on the different
islands were identical. |
____ 155. Darwin began to formulate his
concept of evolution by natural selection after
|
a. |
experimentation with animals. |
|
b. |
observations of many species and their
geographical location. |
|
c. |
reading the writings of Wallace. |
|
d. |
agreeing with Lamarck about the driving
force behind evolution. |
____ 156. James Hutton’s and Charles Lyell’s
work suggests that
|
a. |
Earth is many millions of years old. |
|
b. |
Earth is several thousand years old. |
|
c. |
all fossils were formed in the last 1000
years. |
|
d. |
all rocks on Earth contain fossils. |
____ 157. In the 1800s, Charles Lyell
emphasized that
|
a. |
the human population will outgrow the
available food supply. |
|
b. |
all populations evolve through natural
selection. |
|
c. |
Earth is a few thousand years old. |
|
d. |
past geological events must be explained
in terms of processes observable today. |
____ 158. One scientist who attempted to
explain how rock layers form and change over time was
|
a. |
Thomas Malthus. |
|
b. |
James Hutton. |
|
c. |
Charles Darwin. |
|
d. |
Jean-Baptiste Lamarck. |
____ 159. James Hutton’s and Charles Lyell’s
work was important to Darwin because these scientists
|
a. |
explained volcanoes and earthquakes. |
|
b. |
explained all geologic events on Earth. |
|
c. |
suggested that Earth was old enough for
evolution to have occurred. |
|
d. |
refuted the work of Lamarck, which was
based on misunderstandings. |
____ 160. What did Charles Darwin learn from
reading the work of James Hutton and Charles Lyell?
|
a. |
Earth is relatively young. |
|
b. |
Earth is very old. |
|
c. |
All geological change is caused by
living organisms. |
|
d. |
The processes that formed old rocks on
Earth do not operate today. |
____ 161. Jean-Baptiste Lamarck proposed that
organisms
|
a. |
have an innate tendency toward
complexity and perfection. |
|
b. |
have an innate tendency to become
simpler as time passes. |
|
c. |
inherit all of the adaptations they
display. |
|
d. |
belong to species that never change. |
____ 162. Which is a major concept included in
Lamarck’s theory of evolution?
|
a. |
Change is the result of survival of the
fittest. |
|
b. |
Body structure can change according to
the actions of the organism. |
|
c. |
Population size decreases the rate of
evolution. |
|
d. |
Artificial selection is the basis for
evolution. |
____ 163. Lamarck’s theory of evolution
includes the concept that new organs in a species appear as a result of
|
a. |
continual increases in population size. |
|
b. |
the actions of organisms as they use or
fail to use body structures. |
|
c. |
an unchanging local environment. |
|
d. |
the natural variations already present
within the population of organisms. |
____ 164. In each generation, the wings of
experimental fruit flies were clipped short for fifty generations. The
fifty-first generation emerged with normal-length wings. This observation would
tend to disprove the idea that evolution is based on
|
a. |
inheritance of natural variations. |
|
b. |
inheritance of acquired characteristics. |
|
c. |
natural selection. |
|
d. |
survival of the fittest. |
____ 165. The economist Thomas Malthus
suggested that
|
a. |
in the human population, people die
faster than babies are born. |
|
b. |
there would soon be insufficient food
for the growing human population. |
|
c. |
in the 1700s, England needed more
housing. |
|
d. |
the majority of a species’ offspring
die. |
____ 166. The idea that only famine, disease,
and war could prevent the endless growth of human populations was presented by
|
a. |
Charles Darwin. |
|
b. |
Jean-Baptiste Lamarck. |
|
c. |
Thomas Malthus. |
|
d. |
Charles Lyell. |
____ 167. Darwin realized that the economist
Malthus’s theory of population control
|
a. |
applied only to humans. |
|
b. |
could be generalized to any population
of organisms. |
|
c. |
could be generalized only when
populations lived in crowded conditions. |
|
d. |
explained why the number of deaths
exceeded that of births. |
____ 168. In 1859, Charles Darwin published
his revolutionary scientific ideas in a work titled
|
a. |
Principles of Geology. |
|
b. |
Essay on the Principle of Population. |
|
c. |
Evolution in Malaysia. |
|
d. |
On the Origin of Species. |
____ 169. Darwin was prompted to publish his
theory of evolution by
|
a. |
an essay by Wallace on evolution. |
|
b. |
the publication of Lamarck’s theory of
evolution. |
|
c. |
the vice governor of the Galápagos
Islands. |
|
d. |
the work of Hutton and Lyell. |
____ 170. When Charles Darwin returned from
the voyage of the Beagle, he
|
a. |
immediately published his ideas about
evolution. |
|
b. |
realized his ideas about evolution were
wrong. |
|
c. |
wrote about his ideas but waited many
years to publish them. |
|
d. |
copied the evolutionary theory of
Wallace. |
____ 171. Why might Darwin have hesitated to
publish his concept of evolution by natural selection?
|
a. |
He realized it was not supported by his
data. |
|
b. |
He felt it was too similar to Lamarck’s
to be considered original. |
|
c. |
He was disturbed by his findings, which
challenged fundamental scientific beliefs. |
|
d. |
He realized that his idea was
contradicted by the work of Hutton and Lyell. |
____ 172. When a farmer breeds only his or her
best livestock, the process involved is
|
a. |
natural selection. |
|
b. |
artificial selection. |
|
c. |
artificial variation. |
|
d. |
survival of the fittest. |
____ 173. According to Darwin’s theory of
natural selection, individuals who survive are the ones best adapted for their
environment. Their survival is due to the
|
a. |
possession of adaptations developed
through use. |
|
b. |
possession of inherited adaptations that
maximize fitness. |
|
c. |
lack of competition within the species. |
|
d. |
choices made by plant and animal
breeders. |
____ 174. When farmers select animals or
plants to use for breeding, they look for
|
a. |
species that are perfect and unchanging. |
|
b. |
homologous structures. |
|
c. |
traits that are produced artificially. |
|
d. |
natural variations that are present in a
species. |
____ 175. An adaptation is an inherited
characteristic that can be
|
a. |
physical or behavioral. |
|
b. |
physical or geographical. |
|
c. |
acquired during the organism’s lifetime. |
|
d. |
the result of artificial selection. |
____ 176. When lions prey on a herd of
antelopes, some antelopes are killed and some escape. Which part of Darwin’s
concept of natural selection might be used to describe this situation?
|
a. |
acquired characteristics |
|
b. |
reproductive isolation |
|
c. |
survival of the fittest |
|
d. |
descent with modification |
____ 177. Which statement about the members of
a population that live long enough to reproduce is consistent with the theory
of natural selection?
|
a. |
They transmit characteristics acquired
by use and disuse to their offspring. |
|
b. |
They tend to produce fewer offspring
than others in the population. |
|
c. |
They are the ones that are best adapted
to survive in their environment. |
|
d. |
They will perpetuate unfavorable changes
in the species. |
____ 178. Charles Darwin called the ability of
an organism to survive and reproduce in its environment
|
a. |
diversity. |
|
b. |
fitness. |
|
c. |
adaptation. |
|
d. |
evolution. |
____ 179. According to Darwin’s theory of
natural selection, the individuals that tend to survive are those that have
|
a. |
characteristics their parents acquired
by use and disuse. |
|
b. |
characteristics that plant and animal
breeders value. |
|
c. |
the greatest number of offspring. |
|
d. |
variations best suited to the
environment. |
____ 180. Which of the following phrases best
describes the results of natural selection?
|
a. |
the natural variation found in all
populations |
|
b. |
unrelated but similar species living in
different locations |
|
c. |
the changes in the inherited
characteristics of a population |
|
d. |
the struggle for existence undergone by
all living things |

Figure 15-1
____ 181. In humans, the pelvis and femur, or
thigh bone, are involved in walking. In whales, the pelvis and femur shown in
Figure 15-1 are
|
a. |
examples of fossils. |
|
b. |
vestigial structures. |
|
c. |
acquired traits. |
|
d. |
examples of natural variation. |
____ 182. Charles Darwin’s observation that
finches of different species on the Galápagos Islands have many similar
physical characteristics supports the hypothesis that these finches
|
a. |
have the ability to interbreed. |
|
b. |
acquired traits through use and disuse. |
|
c. |
all eat the same type of food. |
|
d. |
originated from a common ancestor. |
____ 183. Modern sea star larvae resemble some
primitive vertebrate larvae. This similarity may suggest that primitive
vertebrates
|
a. |
share a common ancestor with sea stars. |
|
b. |
evolved from sea stars. |
|
c. |
evolved before sea stars. |
|
d. |
belong to the same species as sea stars. |
____ 184. Darwin’s concept of evolution was
NOT influenced by
|
a. |
the work of Charles Lyell. |
|
b. |
knowledge about the structure of DNA. |
|
c. |
his collection of specimens. |
|
d. |
his trip on the H.M.S. Beagle. |
____ 185. People of Charles Darwin’s time
understood that fossils
|
a. |
were preserved remains of ancient
organisms. |
|
b. |
were available for every organism that
ever lived. |
|
c. |
were unrelated to living species. |
|
d. |
were evidence for the evolution of live
on Earth. |
____ 186. The number and location of bones of
many fossil vertebrates are similar to those in living vertebrates. Most
biologists would probably explain this fact on the basis of
|
a. |
the needs of the organisms. |
|
b. |
a common ancestor. |
|
c. |
the struggle for existence. |
|
d. |
the inheritance of acquired traits. |
____ 187. Charles Darwin viewed the fossil
record as
|
a. |
evidence that Earth was thousands of
years old. |
|
b. |
a detailed record of evolution. |
|
c. |
interesting but unrelated to the
evolution of modern species. |
|
d. |
evidence that traits are acquired
through use or disuse. |
____ 188. The hypothesis that species change
over time by natural selection was proposed by
|
a. |
James Hutton. |